Retail item

Self-Replicating Tissue

Self-Replicating Tissue drops from Guardian of the First Ones in Sanctum of Domination.

Stats and price Where it comes from

Stats and price

The item, as the game shows it.

Its tooltip, and its price on the auction house when it’s traded there.

Sources

Where it comes from.

From the adventure guide’s loot tables and quest rewards.

Dropped by: Guardian of the First OnesSanctum of Domination

Source

Where this data comes from.

Read from Blizzard's official World of Warcraft API.

Data from Blizzard’s official World of Warcraft API, retrieved Oct 5, 2026, 3:07 PM UTC. World of Warcraft and its game data are © Blizzard Entertainment, Inc. NeedBeforeGreed isn’t affiliated with or endorsed by Blizzard.

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